2-Nitrobenzyl alcohol Chemical Properties

Melting point:

69-72 °C(lit.)

Boiling point:

270 °C(lit.)

Density 

1.3386 (rough estimate)

refractive index 

1.5030 (estimate)

Flash point:

168°C/20mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

Crystalline Powder

pka

13.77±0.10(Predicted)

color 

Beige to beige-brown

Water Solubility 

Soluble in water 5000 mg/L 20 deg Celsius.

Sensitive 

Light Sensitive

BRN 

2046649

InChIKey

BWRBVBFLFQKBPT-UHFFFAOYSA-N

CAS DataBase Reference

612-25-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzenemethanol, 2-nitro-(612-25-9)

Safety Information

Hazard Codes 

Xi,C,F

Risk Statements 

11-34

Safety Statements 

22-24/25-45-36/37/39-26-16

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

DP0657050

Hazard Note 

Irritant

HS Code 

29062900

MSDS

• Language:English Provider:2-Nitrobenzyl alcohol
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Nitrobenzyl alcohol Usage And Synthesis

Uses

2-Nitrobenzyl alcohol is a useful research chemical.

Chemical Properties

white to light yellow crystal powde

Uses

The o-nitrobenzyl group (o-NB) is utilized frequently in polymer and materials science. It covers the use of based cross-linkers for photodegradable hydrogels, o-NB side chain functionalization in (block) copolymers, o-NB side chain functionalization for thin film patterning, o-NB for self-assembled monolayers, photo cleavable block copolymers, and photo cleavable bioconjugates.

Synthesis

GENERAL METHODS: The substrate (1 mmol, CAS: 62673-13-6) was mixed with ionic liquid [Dsim]HSO4 (6.5 mg, ~0.02 mmol) in methanol (2 mL) and the reaction was stirred at room temperature. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by evaporation and water (1 mL) was added to the residue with vigorous stirring. The almost pure o-nitrobenzyl alcohol product was obtained by decantation separation. The structure of the product was characterized by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR) data. The ionic liquid was recovered for reuse after vacuum drying at 65 °C to remove water.

storage

Light-sensitive. Harmful if swallowed or inhaled.

References

[1] Bulletin of the Chemical Society of Japan, 2000, vol. 73, # 12, p. 2775 - 2778
[2] Journal of Molecular Catalysis A: Chemical, 2012, vol. 365, p. 15 - 23
[3] Journal of Chemical Research, 2006, # 1, p. 29 - 31
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 1, p. 168 - 177
[5] Journal of the Chinese Chemical Society, 2008, vol. 55, # 5, p. 943 - 946

2-Nitrobenzyl alcohol(612-25-9)Related Product Information

• Ethyl acetate
• 2-Nitrobenzenesulfenyl chloride
• 4-Nitrobenzoic acid
• 4-Hydroxybenzyl alcohol
• Benzhydrol
• Benzyl alcohol
• Triphenylmethanol
• 2-Nitrobenzenesulfonamide
• 2-Nitrobenzoic acid
• Sodium 3-nitrobenzenesulphonate
• 2-Methyl-1-phenyl-2-propanol
• 1-Chloro-3-nitrobenzene
• 4-Methylbenzyl alcohol
• 2-Nitrophenylacetic acid
• 2-Nitrophenylacetonitrile
• 2-Nitrobenzaldehyde
• 2-Nitroacetophenone
• 2-Nitrophenol Sodium Salt