NICLOFOLAN
NICLOFOLAN Basic information
- Product Name:
- NICLOFOLAN
- Synonyms:
-
- NICLOFOLAN
- Niclofoian
- 1'-biphenyl)-2,2'-diol, 5,5'-dichloro-3,3'-dinitro-(
- 3,3'-dichloro-5,5'-dinitro-o,o'-biphenol
- 4,4'-dichloro-6,6'-dinitro-o,o'-biphenol
- 5,5'-dichloro-2,2'-dihydroxy-3,3'-dinitrobiphenyl
- 5,5'-dichloro-3,3'-dinitro(1,1'-biphenyl)-2,2'-diol
- menichlopholan
- CAS:
- 10331-57-4
- MF:
- C12H6Cl2N2O6
- MW:
- 345.09
- EINECS:
- 233-720-0
- Product Categories:
-
- API
- Mol File:
- 10331-57-4.mol
NICLOFOLAN Chemical Properties
- Boiling point:
- 251.5°C (rough estimate)
- Density
- 1.8594 (rough estimate)
- refractive index
- 1.7350 (estimate)
- pka
- 4.34±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- EPA Substance Registry System
- Niclofolan (10331-57-4)
NICLOFOLAN Usage And Synthesis
Chemical Properties
Orange-yellow crystalline powder. Melting point 178-182 ℃. Soluble in acetone, glacial acetic acid and sodium hydroxide solution, slightly soluble in water and ethanol.
Uses
Niclofolan can be used as deworming drug and anti-creep drug. It is used for prevention and treatment of hepatic chioniasis of cattle and sheep.
Definition
ChEBI: Niclofolan is a polychlorobiphenyl.
Synthesis
Niclofolan is obtained by nitration of 5,5 '-dichloro-2, 2' dihydroxybiphenyl. The nitration was carried out in acetic acid at a temperature not exceeding 20℃. Then activated carbon was added for reflux decolorization for 1h. The filter was pumped with a nitrate filter rod. The filtrate was cooled below 15℃ and crystallized. Dinitrochlorophenol was obtained by filtration, washing with acetic acid and drying. The yield is 60%.
NICLOFOLAN Preparation Products And Raw materials
Raw materials
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NICLOFOLAN(10331-57-4)Related Product Information
- Ferric nitrate nonahydrate
- Erbium(III) nitrate pentahydrate
- Cobaltous nitrate hexahydrate
- Nitrazine Yellow
- Ceric ammonium nitrate
- Isosorbide dinitrate
- Sodium nitroprusside dihydrate
- Lanthanum(III) nitrate hexahydrate
- THORIUM NITRATE HYDRATE
- ZIRCONIUM DINITRATE OXIDE
- Nitroclofene
- CERIUM(III) NITRATE HEXAHYDRATE
- Ferric nitrate
- LANTHANUM NITRATE
- Lithium nitrate
- MERCUROUS NITRATE
- NICLOFOLAN
- 5-chloro[1,1'-biphenyl]-2-ol