2'-Hydroxy-3-phenylpropiophenone Chemical Properties

Melting point:

36-37 °C(lit.)

Boiling point:

158°C/2mmHg(lit.)

Density 

1.150±0.06 g/cm3(Predicted)

refractive index 

n20/D 1.5968(lit.)

Flash point:

>230 °F

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly)

form 

Solid

pka

8.07±0.30(Predicted)

color 

Off-White

λmax

324nm(MeOH)(lit.)

CAS DataBase Reference

3516-95-8(CAS DataBase Reference)

EPA Substance Registry System

1-Propanone, 1-(2-hydroxyphenyl)-3-phenyl- (3516-95-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

2914390090

MSDS

• Language:English Provider:SigmaAldrich

2'-Hydroxy-3-phenylpropiophenone Usage And Synthesis

Chemical Properties

Slightly Yellow Crystals

Uses

2’-Hydroxy-3-phenylpropiophenone (Propafenone EP Impurity A; Propafenone BP Impurity A; Propafenone USP Impurity A) is a metabolite of Propafenone (P757500).

General Description

2′-Hydroxy-3-phenylpropiophenone is a colorless to yellow liquid or solid. 2′-Hydroxy-3-phenylpropiophenone derivatives show antiarrhythmic,spasmolytic and local anaesthetic activities.

2'-Hydroxy-3-phenylpropiophenone(3516-95-8)Related Product Information

• FLAVANONE
• N-Despropyl Propafenone Hydrochloride
• 4'-Hydroxy propafenone HCl
• (R)-Propafenone
• Propafenone IMpurity H (EP/BP/USP)
• N-Depropyl N-Benzyl Propafenone
• 1-[5-hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one:hydrochloride
• (S)-Propafenone
• 5-Hydroxy Propafenone Sulfate
• 3-Chloro-1,2-propanediol
• 4-Hydroxy Propafenone Hydrochloride
• Propafenone EP Impurity F
• 2'-(Oxiranylmethoxy)-3-phenylpropiophenon
• Propafenone EP Impurity D
• Propafenone Related Compound B ((2E)-1-[2-[(2RS)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylprop-2-en-1-one)
• Propafenone IMpurity G
• DepropylaMino Chloro Propafenone
• (R)-5-Hydroxy Propafenone Hydrochloride