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Olaquindox

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Olaquindox Basic information

Product Name:
Olaquindox
Synonyms:
  • N-(2-HYDROXYETHYL)-3-METHYL-2-QUINOXALINECARBOXAMIDE 1,4-DIOXIDE
  • OLAGUINDOX
  • OLAQUINDOX
  • 2-(n-(2-hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid
  • 2-quinoxalinecarboxamide,n-(2-hydroxyethyl)-3-methyl-,1,4-dioxide
  • bayernox
  • bayonox
  • bisergon
CAS:
23696-28-8
MF:
C12H13N3O4
MW:
263.25
EINECS:
245-832-7
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • pharma raw material
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Food and Feed Additive
  • Nitric Oxide Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Inhibitors
  • Alkaloids
Mol File:
23696-28-8.mol
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Olaquindox Chemical Properties

Melting point:
209°C (dec.)
Boiling point:
406.49°C (rough estimate)
Density 
1.2755 (rough estimate)
refractive index 
1.5290 (estimate)
storage temp. 
0-6°C
solubility 
DMSO (Slightly)
form 
Solid
pka
13.75±0.10(Predicted)
color 
Yellow
CAS DataBase Reference
23696-28-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-43-42
Safety Statements 
36/37-22
RTECS 
VD1582000
HS Code 
29339900
Hazardous Substances Data
23696-28-8(Hazardous Substances Data)

MSDS

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Olaquindox Usage And Synthesis

Description

Olaquindox is an antibacterial derivative of quinoxaline, used as a growth promoter for pigs.

Description

Olaquindox is an antibiotic and a swine growth regulator. In vivo, olaquindox (100 mg/kg) decreases E. coli-induced diarrhea and the number of intraepithelial lymphocytes in the ileum and increases body weight in geld piglets. Olaquindox induces bleeding, intramuscular edema, vacuolar degeneration, and deformation of renal tubules in C. carpio. It decreases mean body weight and increases the number of dead fetuses in pregnant rats when administered at a dose of 110 mg/kg and increases the number of external deformities, including bent tail, craniorachischisis, exencephaly, and anophthalmia in rat pups born to exposed pregnant mothers. Formulations containing olaquindox have been used as growth promoting agents in bovine livestock.

Chemical Properties

Pale Yellow Crystalline Solid

Uses

A growth stimulant

Uses

It can be found in Bayo-N-Ox and Proquindox and numerous oilier pig feed. It is a photosensitizer and forms a reactive oxyziridine on exposure to light. It can also induce photo allergie contact dermatitis and persistent light reactions in pig breeders.

Uses

Olaquindox is a growth promotor in pig-breeding; acts as a chemotherapeutic agent prophylactically used to lower the frequency of bacterial enteritis in pigs.

Definition

ChEBI: Olaquindox [BAN:INN] is a quinoxaline derivative.

Contact allergens

Olaquindox is an antibacterial agent derivative of quinoxaline, used as a growth promoter of pigs. It can be found in Bayo-N-Ox? and Proquindox? and numerous other pig feeds. It is a photosensitizer that forms reactive photoproducts on light exposure. It can induce photoallergic contact dermatitis and persistent light reactions.

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