Fmoc-O-trityl-L-threonine Chemical Properties

Boiling point:

753.0±60.0 °C(Predicted)

Density 

1.241±0.06 g/cm3(Predicted)

storage temp. 

Store at -15°C to -25°C.

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

3.31±0.10(Predicted)

CAS DataBase Reference

133180-01-5(CAS DataBase Reference)

Safety Information

HS Code 

2924297099

Fmoc-O-trityl-L-threonine Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

General Description

The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].

The product number for this product was previously 04-12-1141.

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Fmoc-O-trityl-L-threonine(133180-01-5)Related Product Information

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