4-Bromo-alpha-phenethylamine Chemical Properties

Boiling point:

140-145°C 30mm

Density 

1.397 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.566(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

clear liquid

pka

8.82±0.10(Predicted)

color 

Colorless to Light yellow to Light orange

Specific Gravity

1.397

Sensitive 

Air Sensitive

BRN 

2412318

CAS DataBase Reference

24358-62-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2735 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29214990

MSDS

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4-Bromo-alpha-phenethylamine Usage And Synthesis

Chemical Properties

Clear colorless liquid

Uses

4-Bromo-α-methylbenzylamine acid may be used in chemical synthesis studies.

Synthesis

Benzaldehyde oxime (CAS: 59862-55-4, 0.121 g, 1 mmol) was used as a starting material and mixed with nano Fe3O4 (0.046 g, 0.2 mmol, nanoparticle size of about 70 nm) to be ground in a porcelain mortar. Subsequently, ZrCl4 (0.233 g, 1 mmol) was added and the mixture was continued to be ground to homogeneity at room temperature. The mixture was transferred to an oil bath and heated to 75-80°C. At this temperature, NaBH3CN (0.314 g, 5 mmol) was added in batches and the reaction mixture was continuously ground at 75-80 °C for 15 min. Upon completion of the reaction, the reaction was quenched by the addition of H2O (5 mL) and stirred for 5 min. The reaction mixture was extracted with EtOAc (2 x 5 mL) and the organic phases were combined and dried over anhydrous Na2SO4. The solvent was evaporated under reduced pressure to give pure liquid 1-(4-bromophenyl)ethylamine in 93% yield (0.1 g, see Table 2, entry 1).

References

[1] Journal of the Iranian Chemical Society, 2015, vol. 12, # 5, p. 873 - 878
[2] Journal of the American Chemical Society, 1952, vol. 74, p. 5185
[3] Journal of Organic Chemistry, 1955, vol. 20, p. 1757,1758,1759

4-Bromo-alpha-phenethylamine(24358-62-1)Related Product Information

• L-1-Phenylethylamine
• Decabromodiphenyl Ethane
• 1,2-Dichloroethane
• Diethylstilbestrol
• ETHANE
• Glycine
• 2-Phenylethylamine hydrochloride
• Tyramine
• 6-Aminocaproic acid
• DL-ALPHA-METHYLBENZYLAMINE
• Ethylamine
• ALTRENOGEST
• Hexafluoroethane
• Tris(hydroxymethyl)aminomethane
• Bromine
• D/L-AMPHETAMINE HYDROCHLORIDE
• Propiophenone
• (+/-)-1-(4-BROMOPHENYL)ETHYL ISOCYANATE