Basic information Safety Supplier Related

PHOLCODINE

Basic information Safety Supplier Related

PHOLCODINE Basic information

Product Name:
PHOLCODINE
Synonyms:
  • (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol
  • 3-(2-(4-Morpholinyl)ethyl)morphine
  • 3-(2-Morpholinoethyl)morphine
  • 3-Morpholylaethylmorphin
  • 3-o-(2-morpholinoethyl)-morphin
  • 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-al
  • 7,8-Didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-alpha-ol
  • beta-Morpholinoethylmorphine
CAS:
509-67-1
MF:
C23H30N2O4
MW:
398.5
EINECS:
208-102-9
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
Mol File:
509-67-1.mol
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PHOLCODINE Chemical Properties

Melting point:
91°C
Boiling point:
521.67°C (rough estimate)
Density 
1.1772 (rough estimate)
refractive index 
1.6300 (estimate)
solubility 
Sparingly soluble in water, freely soluble in acetone and in ethanol (96 per cent). It dissolves in dilute mineral acids.
form 
Solid
pka
pKa 5.30(50% aq EtOH) (Uncertain)
color 
Light Brown
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Safety Information

Toxicity
LD50 oral in mouse: 1gm/kg
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PHOLCODINE Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

antimalarial derivative of natural artemisinin

Uses

Antitussive; an opioid cough suppressant. Controlled Substance.

Definition

ChEBI: A morphinane alkaloid that is a derivative of morphine with a 2-morpholinoethyl group at the 3-position.

brand name

Ethnine Simplex (Purdue Frederick).

PHOLCODINESupplier

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PHOLCODINE(509-67-1)Related Product Information