XANTHOQUINODIN A1
XANTHOQUINODIN A1 Basic information
- Product Name:
- XANTHOQUINODIN A1
- Synonyms:
-
- XANTHOQUINODIN A1
- 4aH-7a,15-Ethenonaphtho[2',3':4,5]cyclohepta[1,2-b]xanthene-4a-carboxylic acid, 2,3,4,7,8,13,15,17-octahydro-1,4,12,14,16-pentahydroxy-10-methyl-8,13,17-trioxo-, methyl ester, (4R,4aS,7aS,15R)-rel-
- (4R,4aS,7aS,15R)-rel-2,3,4,7,8,13,15,17-octahydro-1,4,12,14,16-pentahydroxy-10-methyl-8,13,17-trioxo-4aH-7a,15-ethenonaphtho[2′,3′:4,5]cyclohepta[1,2-b]xanthene-4a-carboxylic acid, methyl ester
- CAS:
- 151063-27-3
- MF:
- C31H24O11
- MW:
- 572.52
- Mol File:
- 151063-27-3.mol
XANTHOQUINODIN A1 Chemical Properties
- Boiling point:
- 859.6±65.0 °C(Predicted)
- Density
- 1.74±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
- form
- A solid
- pka
- 4.50±1.00(Predicted)
XANTHOQUINODIN A1 Usage And Synthesis
Biological Activity
Xanthoquinodin A1 is a fungal metabolite that has been found in Humicola and has diverse biological activities.1,2 It inhibits E. tenella schizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1 Xanthoquinodin A1 is active against B. subtilis, M. luteus, S. aureus, A. laidlawii, and B. fragilis in a disc assay when used at a concentration of 1 mg/ml. It is also active against B. cereus (MIC = 0.44 μM).2 Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cancer cells.
References
1.Tabata, N., Suzumura, Y., Tomoda, H., et al.Xanthoquinodins, new anticoccidial agents produced by Humicola sp. Production, isolation and physico-chemical and biological propertiesJ. Antibiot. (Tokyo)46(5)749-755(1993) 2.Tantapakul, C., Promgool, T., Kanokmedhakul, K., et al.Bioactive xanthoquinodins and epipolythiodioxopiperazines from Chaetomium globosum 7s-1, an endophytic fungus isolated from Rhapis cochinchinensis (Lour.) MartNat. Prod. Res.34(4)494-502(2020)
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