BIFEMELANE Chemical Properties

Boiling point:

395℃

Density 

1.006

Flash point:

169℃

storage temp. 

Sealed in dry,2-8°C

pka

10.56±0.10(Predicted)

BIFEMELANE Usage And Synthesis

Originator

Bifemelane hydrochloride,ABATRA Technology Co., Ltd.

Definition

ChEBI: N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine is a diarylmethane.

Manufacturing Process

N-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine was prepared from 2- (5-bromopentyloxy)diphenylmethane and of methylamine in ethanol is at 50°C in a sealed tube (heating for 3 hours). Ethanol and excess methylamine are distilled in vacuo, 2 N NaOH aqueous solution is added, and the reaction product is extracted with ether. Dry hydrogen chloride gas is passed into the ether solution, and the precipitate collected by filtration. Recrystallization from ethanol-ether gives N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochloride, m.p. 87.5-89.5°C.

Therapeutic Function

Antidepressant, Antiulcer, Nootropic

Biological Activity

Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

BIFEMELANE(90293-01-9)Related Product Information

• Diclofenac sodium
• Allene
• N-METHYLBUTYLAMINE
• 2-BENZYL-4-CHLOROPHENYL 4-PIPERIDINYLMETHYL ETHER
• 3-(2-BENZYLPHENOXY)PIPERIDINE
• BIFEMELANE
• 4-[(2-BENZYLPHENOXY)METHYL]PIPERIDINEHYDROCHLORIDE
• Bifemelane HCl,Bifemelane hydrochloride