L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Chemical Properties

Melting point:

100-200 °C

storage temp. 

-20°C

solubility 

Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated)

form 

powder

color 

white

Stability:

Hygroscopic, Moisture Sensitive

InChIKey

IHNKQIMGVNPMTC-RUZDIDTESA-N

Safety Information

WGK Germany 

3

HS Code 

2923.90.0100

MSDS

• Language:English Provider:SigmaAldrich

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Usage And Synthesis

Description

Lyso-PC (18:0), also known as 1-stearoyl-sn-glycero-3-phosphocholine, is a lysophosphocoline connceted to hydrophobic fatty acid tail (stearic acid) by a glycerol.

Uses

Stearoyl L-α-Lysolecithin is an bioactive lysophosphatidylcholine derived compound found to be released by bronchial epithelial cells. Stearoyl L-α-Lysolecithin have also been utilized in the development of liposomes and michelles by drug transdermal delivery devices.

Uses

18:0 Lyso PC has been used:

• to functionalize carbon nanotubes (CNTs) for the development of methods to attach DNA to CNTs
• to increase the level of lysophosphatidic acid (LPA) in mouse
• to induce TNF receptor associated factor 3 interacting protein 2 (TRAF3IP2) expression in endothelial cells (EC)

Definition

ChEBI: 1-stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 18:0 in which the acyl substituent is located at position 1 and is specified as stearoyl. It has a role as a mouse metabolite and an apoptosis inducer. It is a 1-O-acyl-sn-glycero-3-phosphocholine and a lysophosphatidylcholine 18:0. It is functionally related to an octadecanoic acid.

Biochem/physiol Actions

1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles.

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