Basic information Safety Supplier Related

1-(4-Fluorophenyl)piperazine

Basic information Safety Supplier Related

1-(4-Fluorophenyl)piperazine Basic information

Product Name:
1-(4-Fluorophenyl)piperazine
Synonyms:
  • FLUOROPHENYL PIPERAZINE
  • TRIFLUOROETHOXY FLUOROPHENYL PIPERAZINE
  • 1-(4-Fluorophenyl)piperazine, 98% 10GR
  • 4-(1-Piperazino)fluorobenzene
  • 1-(4-Fluorophenyl)piperazine 97%
  • 1-(4-Fluorophenyl)piperazine97%
  • 1-(4-Fluorophenyl)piperazine ,98%
  • 4-(4-Fluorophenyl)piperazine
CAS:
2252-63-3
MF:
C10H13FN2
MW:
180.22
EINECS:
218-846-6
Product Categories:
  • Nitrogen cyclic compounds
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Piperidines, Piperidones, Piperazines
  • Piperaizine
  • API intermediates
  • Building Blocks
  • Heterocyclic Building Blocks
  • Piperazines
  • Bioactive Small Molecules
  • Building Blocks
  • C10
  • Cell Biology
  • Chemical Synthesis
  • F
  • Fluorinated Building Blocks
  • Heterocyclic Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • Other Fluorinated Heterocycles
Mol File:
2252-63-3.mol
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1-(4-Fluorophenyl)piperazine Chemical Properties

Melting point:
30-33 °C (lit.)
Boiling point:
118-123 °C/0.1 mmHg (lit.)
Density 
1.0
refractive index 
1.5585-1.5605
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Liquid After Melting
pka
8.93±0.10(Predicted)
color 
Clear yellow
Water Solubility 
Insoluble in water.
Sensitive 
Air Sensitive
BRN 
610723
CAS DataBase Reference
2252-63-3(CAS DataBase Reference)
NIST Chemistry Reference
1-(P-fluorophenyl)piperazine(2252-63-3)
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Safety Information

Hazard Codes 
Xn,T,C
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36
RIDADR 
2811
WGK Germany 
2
Hazard Note 
Toxic/Corrosive
HazardClass 
8
PackingGroup 
III
HS Code 
29339900

MSDS

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1-(4-Fluorophenyl)piperazine Usage And Synthesis

Chemical Properties

clear yellowish liquid after melting

Uses

1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug.

Uses

1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidatio n.

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