2'-Deoxycytidine-5'-monophosphoric acid
2'-Deoxycytidine-5'-monophosphoric acid Basic information
- Product Name:
- 2'-Deoxycytidine-5'-monophosphoric acid
- Synonyms:
-
- 2''-DEOXYCYTIDINE-5''-MONOPHOSPHATE (WRITE CRYSTALLINE POWDER 98-100%)
- 5''-CYTIDYLIC ACID, 2''-DEOXY-
- 2''-DEOXYCYTIDINE 5''-MONOPHOSPHATE FREE ACID (DCMP)
- 2'-Deoxycytidine 5'-Monophosphate Hydrate
- dCMP, Deoxycytidylic acid
- 2'-Deoxycytidine-5'-monpohosphate free acid
- dCMP.H2
- (2R)-4-(Phosphonomethyl)piperazine-2-carboxylic acid
- CAS:
- 1032-65-1
- MF:
- C9H14N3O7P
- MW:
- 307.2
- EINECS:
- 213-849-9
- Product Categories:
-
- Nucleic acids
- Bases & Related Reagents
- Pyridines, Pyrimidines, Purines and Pteredines
- Biochemistry
- Nucleosides, Nucleotides & Related Reagents
- Nucleotides and their analogs
- Carbohydrates & Derivatives
- Heterocycles
- Nucleotides
- Phosphorylating and Phosphitylating Agents
- Nucleotide
- Mol File:
- 1032-65-1.mol
2'-Deoxycytidine-5'-monophosphoric acid Chemical Properties
- Melting point:
- 169-172 °C (dec.)
- Boiling point:
- 633.8±65.0 °C(Predicted)
- Density
- 2.01±0.1 g/cm3(Predicted)
- refractive index
- 37 ° (C=1, H2O)
- storage temp.
- -20°C
- solubility
- H2O: 10 mg/mL, clear, colorless
- form
- Crystalline Powder
- pka
- 1.86±0.10(Predicted)
- color
- White
- Water Solubility
- Soluble in water.
- BRN
- 41062
- CAS DataBase Reference
- 1032-65-1(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 22-24/25-37/39-36-26
- WGK Germany
- 3
- F
- 10-21
- HS Code
- 29349990
MSDS
- Language:English Provider:2'-Deoxycytidine-5'-monophosphoric acid
- Language:English Provider:SigmaAldrich
2'-Deoxycytidine-5'-monophosphoric acid Usage And Synthesis
Chemical Properties
Crystalline
Uses
A phosphorylated metabolite of the deoxyribonucleoside 2’Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferatio n.
Uses
2'-Deoxycytidine-5'-monophosphate is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis.
Definition
ChEBI: Dianion of 2'-deoxycytidine 5'-monophosphate arising from deprotonation of both OH groups of the phosphate.
General Description
2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′.
Purification Methods
Recrystallise the acid from H2O or aqueous EtOH and dry it in a vacuum. [Volkin et al. J Am Chem Soc 73 1533 1951, UV: Fox et al. J Am Chem Soc 75 4315 1953, IR: Michelson & Todd J Chem Soc 3438 1954, Beilstein 25 IV 3664.]
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2'-Deoxycytidine-5'-monophosphoric acid(1032-65-1)Related Product Information
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- MOPSO
- Ethyl 2-(Chlorosulfonyl)acetate
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- Cytidine-5'-triphosphate disodium salt dihydrate
- Citric acid
- Stearic acid
- 5-Azacytidine
- 2'-Deoxycytidine
- Cytidine 5’-monophosphate
- Ascoric Acid
- 2'-Deoxycytidine-5'-triphosphoric acid disodium salt
- CDP
- Cytidine 5′-(tetrahydrogen triphosphate), xsodium salt, hydrate
- 2'-Deoxycytidine-5'-diphosphate trisodium salt
- ARA-CMP
- Cytidine 5'-monophosphate disodium salt