(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Chemical Properties

Boiling point:

182 °C(lit.)

Density 

1.093 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.451(lit.)

Flash point:

185 °F

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly)

form 

Oil

color 

Colourless

InChIKey

QGMROEZDWJTIDW-UHFFFAOYSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

TSCA 

No

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Usage And Synthesis

Uses

The propanol functionality of this versatile reagent can be introduced to many pharmaceuticals.1,2,3,4

Uses

(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.
It may be used as an alkylating agent in the synthesis of the following:

• N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide
• O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester
• tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane

Uses

(3-Bromopropoxy)-tert-butyldimethylsilane is a reagent in the preparation of piperidinylcarbonyl sulfamates as a novel class of antihyperlipidemic agents with LDL-receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.

General Description

(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE(89031-84-5)Related Product Information

• T-BUTYLDIMETHYLSILANE
• TRANS-3-BROMO-5-TERT-BUTYL-DIMETHYLSILYLOXY-2-PENTEN-1-OL
• (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE