1,9-DIDEOXYFORSKOLIN Chemical Properties

Melting point:

149-150℃

storage temp. 

−20°C

solubility 

methanol: 28 mg/mL

form 

solid

color 

white

optical activity

[α]26/D +93.6°, c = 6.12 in chloroform(lit.)

InChIKey

ZKZMDXUDDJYAIB-OJPJTMFRSA-N

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

1,9-DIDEOXYFORSKOLIN Usage And Synthesis

Description

Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.

Uses

1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

Definition

ChEBI: A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin.

1,9-DIDEOXYFORSKOLIN(64657-18-7)Related Product Information

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