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1-Methylindazole-3-carboxylic acid

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1-Methylindazole-3-carboxylic acid Basic information

Product Name:
1-Methylindazole-3-carboxylic acid
Synonyms:
  • 1-Methylindazole-3-carbox...
  • Granisetron Related Compound D (15 mg) (1-methyl-1H-indazole-3-carboxylic acid)
  • 1-Methyl INDAZOLE 3,CARBOXILIC ACID
  • Methyl-1H-indazole-3-carboxyl
  • 1-Methylindazole-3-carboxylicacid,97%
  • 1-Methylindazole-3-carboxylic acid 97%
  • 1-Methyl-1H-indazol-3-carboxylic acid
  • 1-METHYLINDAZOLE-3-CARBOXYLIC ACID
CAS:
50890-83-0
MF:
C9H8N2O2
MW:
176.17
EINECS:
626-233-3
Product Categories:
  • Heterocycles, Impurities, Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
  • Intermediates & Fine Chemicals
  • Indoles and derivatives
  • Impurities
  • Indole Derivatives
  • Pharmaceuticals
  • pharmacetical
  • Benzene derivates
  • Organic acids
  • Carboxylic Acids
  • Fused Ring Systems
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indazoles
  • Acids and Derivatives
  • Heterocycles
  • Carboxylic Acids
  • (intermediate of granisetron)
Mol File:
50890-83-0.mol
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1-Methylindazole-3-carboxylic acid Chemical Properties

Melting point:
213 °C
Boiling point:
383.7±15.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.14±0.10(Predicted)
form 
Solid
color 
White to Off White
Water Solubility 
Insoluble in water. Soluble in DMSO and Methanol.
InChI
InChI=1S/C9H8N2O2/c1-11-7-5-3-2-4-6(7)8(10-11)9(12)13/h2-5H,1H3,(H,12,13)
InChIKey
OVVDFORZEGKEJM-UHFFFAOYSA-N
SMILES
N1(C)C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference
50890-83-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36-36/37/38
Safety Statements 
26-36/37/39-22
WGK Germany 
3
Hazard Note 
Harmful
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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1-Methylindazole-3-carboxylic acid Usage And Synthesis

Chemical Properties

Off White Solid

Uses

1-Methylindazole-3-carboxylic acid is used as important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as a pharmaceutical adjuvant, Granisetron Impurity D.

Uses

Granisetron Impurity D.

Synthesis Reference(s)

The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o

1-Methylindazole-3-carboxylic acid Preparation Products And Raw materials

Raw materials

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