1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Chemical Properties

Melting point:

120-122 °C(lit.)

alpha 

6 º (c=5, Chloroform)

Boiling point:

382.0±32.0 °C(Predicted)

Density 

1.175±0.06 g/cm3(Predicted)

refractive index 

6.5 ° (C=8, CHCl3)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

methanol: 100 mg/mL, clear, colorless

form 

Crystalline Powder

pka

12.98±0.20(Predicted)

color 

White

optical activity

[α]/D +6.0±1.0°, c = 5 in chloroform

BRN 

83765

InChI

1S/C12H22O6/c1-11(2)15-5-7(17-11)9(13)10(14)8-6-16-12(3,4)18-8/h7-10,13-14H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1

InChIKey

ODYBCPSCYHAGHA-ZYUZMQFOSA-N

SMILES

CC1(C)OC[C@@H](O1)[C@@H](O)[C@H](O)[C@H]2COC(C)(C)O2

CAS DataBase Reference

1707-77-3(CAS DataBase Reference)

NIST Chemistry Reference

D-Mannitol, 1,2:5,6-bis-o-(1-methylethylidene)-(1707-77-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36/37-26

WGK Germany 

3

F 

10-21

HS Code 

29329990

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Usage And Synthesis

Chemical Properties

White Solid

Uses

Nebivolol intermediate.

Purification Methods

Although quite soluble in H2O, it gives a purer product when crystallised from this solvent, forming needles [Baer J Am Chem Soc 67 338 1945, NMR: Curtis et al. J Chem Soc, Perkin Trans 1 1756 1977]. [Beilstein 19/11 V 589.]

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol(1707-77-3)Related Product Information

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• Mannitol
• Dimethyl sulfide
• Dimethyl ether
• D-Mannitol
• Dimethyl fumarate
• Dimethyl carbonate
• Diacetone acrylamide
• Diacetone Alcohol
• ETHANE
• Diacetone-D-glucose
• 4-METHYL-1,3-DIOXOLANE
• 1,2,6-Hexanetriol
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