2-Bromo-5-nitrothiazole Chemical Properties

Melting point:

85-88 °C (dec.) (lit.)

Boiling point:

289.7±13.0 °C(Predicted)

Density 

2.1273 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

-2.84±0.10(Predicted)

form 

Crystalline Powder

color 

Yellow to brown

Water Solubility 

Slightly soluble in water.

BRN 

4856

InChI

InChI=1S/C3HBrN2O2S/c4-3-5-1-2(9-3)6(7)8/h1H

InChIKey

ANIJFZVZXZQFDH-UHFFFAOYSA-N

SMILES

S1C([N+]([O-])=O)=CN=C1Br

CAS DataBase Reference

3034-48-8(CAS DataBase Reference)

NIST Chemistry Reference

2-Bromo-5-nitrothiazole(3034-48-8)

EPA Substance Registry System

Thiazole, 2-bromo-5-nitro- (3034-48-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

XJ2986000

TSCA 

Yes

HS Code 

29339900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Bromo-5-nitrothiazole Usage And Synthesis

Chemical Properties

YELLOW TO BROWN CRYSTALLINE POWDER

Uses

2-Bromo-5-nitrothiazole is used as a building block. It is used as an intermediate to produce other chemicals.

Application

The reaction of 2-Bromo-5-nitrothiazole with weakly basic secondary aliphatic amines produces the expected 2-amino product from nucleophilic substitution of bromine. However, the reaction of isomeric 5-bromo-2-nitrothiazole with such amines produces the expected mixture of the 5-amino product and the 2-amino 5-nitrothiazole rearrangement product.

2-Bromo-5-nitrothiazole(3034-48-8)Related Product Information

• 2,2'-Dithiobis(benzothiazole)
• Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
• 4-Nitrobenzyl bromide
• 2-Mercaptobenzothiazole
• Benzothiazole
• Fosthiazate
• 3-Bromoanisole
• 2-Bromothiazole
• 5-NITRO-1,3-THIAZOLE 96
• Thiazole
• 5-Thiazolamine
• Bromine
• 2-BROMO-4-NITROTHIAZOLE
• 2-Bromo-5-nitrothiazole