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Perfluoropropionic anhydride

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Perfluoropropionic anhydride Basic information

Product Name:
Perfluoropropionic anhydride
Synonyms:
  • Pentafluoropropionic anhydride, PFAA
  • PENTAFLUORPROPIONSUREANHYDRID
  • Pentafluoropropionic anhydride,PFPA, Perfluoropropionic anhydride
  • Perfluoropropanoic anhydride 99%
  • 2,2,3,3,3-Pentafluoropropanoyl 2,2,3,3,3-pentafluoropropanoate
  • Pentafluoropropionic anhydride, min. 97%
  • PENTAFLUORPROPIONSREANHYDRID
  • Bis(2,2,3,3,3-pentafluoropropionic acid)anhydride
CAS:
356-42-3
MF:
C6F10O3
MW:
310.05
EINECS:
206-604-2
Product Categories:
  • organofluorine compounds
  • Analytical and Industrial Enzymes
  • PFPA - Pentafluoropropionic anhydride
  • and Substrates
  • Biochemicals and Reagents
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Chemical Synthesis
  • Enzymes
  • -Glucuronidase
  • -Glucuronidase Drug Analysis Bundle
  • Inhibitors
  • Acylation Reagent
  • Small molecule
  • Acylation (GC Derivatizing Reagents)
  • Analytical Chemistry
  • GC Derivatizing Reagents
  • Organic Building Blocks
Mol File:
356-42-3.mol
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Perfluoropropionic anhydride Chemical Properties

Melting point:
-43
Boiling point:
69-70 °C/735 mmHg (lit.)
Density 
1.571 g/mL at 25 °C (lit.)
refractive index 
1.3
Flash point:
None
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Liquid
color 
Clear colorless
Specific Gravity
1.571
Water Solubility 
Reacts with water.
Sensitive 
Moisture Sensitive
BRN 
1806446
Stability:
Hygroscopic, Moisture Sensitive
InChIKey
XETRHNFRKCNWAJ-UHFFFAOYSA-N
CAS DataBase Reference
356-42-3(CAS DataBase Reference)
NIST Chemistry Reference
Pentafluoropropionic anhydride(356-42-3)
EPA Substance Registry System
Pentafluoropropionic anhydride (356-42-3)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-14
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
10-21
Hazard Note 
Corrosive
TSCA 
T
HazardClass 
8
PackingGroup 
II
HS Code 
29159000

MSDS

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Perfluoropropionic anhydride Usage And Synthesis

Chemical Properties

Perfluoropropionic anhydride is a clear, colorless to light yellow liquid that is highly sensitive to moisture. It undergoes vigorous reactions when exposed to water. It is used in a GC-MS analysis of stereoisomer content of synthetic peptides. It is also utilized in a GC-MS detection method for synephrine in dietary supplements.

Uses

Pentafluoropropionic anhydride act as a derivatising agent of amines and alcohols. It is used in the in preparation of halogenated derivatives of phenolic acids, required for determination of some biologically important acids in cerebrospinal fluid, as derivatization reagent in detection of 1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline as endogenous amines from non-treated rat brain by GC-multiple ion detection and in simultaneous determination of the major metabolites of dopamine in rat striatum by gas-liquid chromatography.

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