3-(Trifluoromethoxy)aniline Chemical Properties

Boiling point:

72-73 °C8 mm Hg(lit.)

Density 

1.325 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.466(lit.)

Flash point:

185 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Liquid

pka

3.36±0.10(Predicted)

Specific Gravity

1.325

color 

Clear yellow to orange

Water Solubility 

Not miscible or difficult to mix in water.

BRN 

776921

CAS DataBase Reference

1535-73-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,T,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-27-36/37/39-36

RIDADR 

2810

WGK Germany 

3

Hazard Note 

Toxic

HazardClass 

IRRITANT, TOXIC

HazardClass 

6.1

HS Code 

29222900

MSDS

• Language:English Provider:3-(Trifluoromethoxy)aniline
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-(Trifluoromethoxy)aniline Usage And Synthesis

Chemical Properties

CLEAR YELLOW LIQUID

Uses

3-(Trifluoromethoxy)aniline is reactant in the synthesis of pyrazolone-quinazolone hybrids as human hydroxyphenylpyruvate dioxygenase inhibitors which is a potential treatment for type I tyrosinemia.

General Description

Synthesis of 3-(trifluoromethoxy)aniline from 2-chlorophenol has been reported.

3-(Trifluoromethoxy)aniline(1535-73-5)Related Product Information

• METHOXYTRIMETHYLSILANE
• p-Anisidine
• (Trifluoromethoxy)benzene
• ANILINE BLACK
• 4-Aminobenzotrifluoride
• 2,3,4-Trimethoxybenzaldehyde
• 3-Aminobenzotrifluoride
• 2-Fluoroaniline
• 4-Fluoroaniline
• Aniline
• 2-Aminobenzotrifluoride
• m-Anisidine
• o-Anisidine
• 3-Methoxyacetophenone
• 4-(Trifluoromethoxy)aniline
• Azoic Diazo Component 1
• 3-(Trifluoromethoxy)nitrobenzene
• 2-(Trifluoromethoxy)aniline