Basic information Safety Supplier Related

TETRAMETHYLURIC ACID

Basic information Safety Supplier Related

TETRAMETHYLURIC ACID Basic information

Product Name:
TETRAMETHYLURIC ACID
Synonyms:
  • Tetramethyluric acid (Theacrine)
  • 1,3,7,8-tetramethyl-1H-purine-2,6(3H,7H)-dione
  • TETRAMETHYLURIC ACID
  • Nano Liposomal TETRAMETHYLURIC ACID
  • 1,3,7,9-Tetramethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
  • 1,3,7,9-Tetramethyluric acid
  • 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3,7,9-tetramethyl-
  • Ba 2750
CAS:
2309-49-1
MF:
C9H12N4O3
MW:
224.22
EINECS:
218-994-1
Product Categories:
  • 2309-49-1
Mol File:
2309-49-1.mol
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TETRAMETHYLURIC ACID Chemical Properties

Melting point:
226℃
Boiling point:
365.61°C (rough estimate)
Density 
1.3055 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-1.93±0.20(Predicted)
color 
White to Off-White
Water Solubility 
33mg/L(room temperature)
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TETRAMETHYLURIC ACID Usage And Synthesis

Uses

Tetramethyluric acid is an impurity of caffeine. Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.

Definition

ChEBI: 1,3,7,9-tetramethyluric acid is an oxopurine that is uric acid in which the hydrogens at positions 1,3,7 and 9 are replaced by methyl groups. It is a purine alkaloid that is found in Chinese tea known as kucha (Camellia assamica var. kucha) and exhibits anti-inflammatory and analgesic properties. It has a role as a plant metabolite, an anti-inflammatory agent, an analgesic and a human xenobiotic metabolite. It is an oxopurine and a purine alkaloid. It is functionally related to a 7,9-dihydro-1H-purine-2,6,8(3H)-trione.

Purification Methods

Crystallise the uric acid from H2O or MeOH. [Beilstein 26 H 532, 26 I 156, 26 II 302, 21 III/IV 2623.]

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