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Fmoc-D-Asn(Trt)-OH

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Fmoc-D-Asn(Trt)-OH Basic information

Product Name:
Fmoc-D-Asn(Trt)-OH
Synonyms:
  • D-Asparagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
  • Nα-Fmoc-Nγ-trityl-D-asparagine≥ 99% (HPLC)
  • N-ALPHA-FMOC-N-BETA-TRITYL-D-ASPARAGINE
  • N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-OMEGA-TRITYL-D-ASPARAGINE
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Asn(Trt)-OH
  • (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoicacid
  • N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-D-asparagine
  • -(4-methyltrityl)-L-2,4-diaminobutyric acid
CAS:
180570-71-2
MF:
C38H32N2O5
MW:
596.67
Product Categories:
  • Asparagine [Asn, N]
  • Fmoc-Amino Acids and Derivatives
  • Amino Acids
  • Fmoc-Amino acid series
Mol File:
180570-71-2.mol
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Fmoc-D-Asn(Trt)-OH Chemical Properties

Melting point:
211-216°C
Boiling point:
858.1±65.0 °C(Predicted)
Density 
1.271±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Sparingly)
pka
3.79±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Acid Sensitive
InChI
InChI=1S/C38H32N2O5/c39-35(41)24-34(36(42)43)40(37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H2,39,41)(H,42,43)/t34-/m1/s1
InChIKey
LEAIJCJTJSTEDG-UUWRZZSWSA-N
SMILES
C(O)(=O)[C@@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference
180570-71-2(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29242990
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Fmoc-D-Asn(Trt)-OH Usage And Synthesis

Description

Fmoc-D-Asn(Trt)-OH is the dextrorotary form of Asparagine, and its side chain is protected by Trt group. D-amino acids are toxic in a variety of animals. However, the study of D-amino acids will contribute to the development of new drugs. Fmoc is often preferred over Boc because of its ease of cleavage

Chemical Properties

White powder

Uses

Fmoc-d-asn(trt)-oh, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Fmoc-D-Asn(Trt)-OHSupplier

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