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2,4-Dimethoxyacetophenone

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2,4-Dimethoxyacetophenone Basic information

Product Name:
2,4-Dimethoxyacetophenone
Synonyms:
  • 2',4'-DIMETHOXYACETOPHENONE
  • 2,4-DIMETHOXYACETOPHENONE
  • 2,4'-Dimethoxyacetaphenone
  • 2',4'-Dimethoxyacethophenone, 98%
  • 1-Acetyl-2,4-dimethoxybenzene
  • 2',4'-Dimethoxyacetophenone,98%
  • AKOS BBS-00004235
  • 1-(2,4-Dimethoxy-phenyl)-ethanone
CAS:
829-20-9
MF:
C10H12O3
MW:
180.2
EINECS:
212-587-2
Product Categories:
  • Building Blocks
  • C10
  • Carbonyl Compounds
  • Chemical Synthesis
  • Ketones
  • Organic Building Blocks
  • Aromatic Acetophenones & Derivatives (substituted)
  • Acetophenone series
  • 829-20-9
Mol File:
829-20-9.mol
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2,4-Dimethoxyacetophenone Chemical Properties

Melting point:
37-40 °C(lit.)
Boiling point:
288 °C(lit.)
Density 
1.1272 (rough estimate)
refractive index 
1.5430 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Dichloromethane, Ethyl Acetate, Methanol
form 
Crystalline Powder
color 
White to off-white
Sensitive 
Light Sensitive
BRN 
511947
CAS DataBase Reference
829-20-9(CAS DataBase Reference)
NIST Chemistry Reference
2',4'-Dimethoxyacetophenone(829-20-9)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29145090

MSDS

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2,4-Dimethoxyacetophenone Usage And Synthesis

Chemical Properties

white to off-white crystalline powder

Uses

2',4'-Dimethoxyacetophenone-d6 is an by-product in the synthesis of Paeonol-d3 (P133842). Paeonol-d3 is a labelled analogue of Paeonol (P133840), acting as a b-Secretase inhibitor an anti-apoptotic agent is used in the treatment of memory loss after ischemic stroke. Anti-inflammatory and analgesic.

Preparation

Obtained by reaction of dimethyl sulfate with resacetophenone in the presence of 10% aqueous sodium hydroxide (61%).

Definition

ChEBI: 2,4-Dimethoxyacetophenone is an aromatic ketone.

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