Ethyl glycolate Chemical Properties

Melting point:

>300 °C

Boiling point:

158-159 °C (lit.)

Density 

1.1 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.419(lit.)

Flash point:

143 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol (Slightly)

pka

13.14±0.10(Predicted)

form 

Liquid

color 

Colorless

Odor

Peculiar ethereal, weedy-winey odour, often classified as "Spearmint-like".

Water Solubility 

It is very soluble in water, alcohols, acetone, acetates, slightly soluble in ethyl ether, sparingly soluble in hydrocarbon solvents, polymerization occurs above 50 C.

InChIKey

ZANNOFHADGWOLI-UHFFFAOYSA-N

CAS DataBase Reference

623-50-7(CAS DataBase Reference)

NIST Chemistry Reference

Acetic acid, hydroxy-, ethyl ester(623-50-7)

EPA Substance Registry System

Acetic acid, hydroxy-, ethyl ester (623-50-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-37/39

RIDADR 

1993

WGK Germany 

3

RTECS 

MC5410000

TSCA 

Yes

HazardClass 

3.2

PackingGroup 

III

HS Code 

29181990

MSDS

• Language:English Provider:Ethyl glycolate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Ethyl glycolate Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

Ethyl glycolate, is an important building block for the preparation of agrochemicals and medicinal compounds. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuff. It is also used in synthetic chemistry, discovery process and R&D. It also can be used as solvents.

Production Methods

The corresponding acid occurs in unripe Grapes. Ethyl glycolate is produced from Ethylene glycol by oxidation to Glycoiiic acid, followed by esterification.

Application

Ethyl glycollate is an important building block for the preparation of medicinal compounds and agrochemicals. It may be used:

• as starting reagent in the synthesis of 2-ferrocenylfuran;
• as substrate during the polycondensation of α-hydroxy acids by enzymes and polyethylene glycol (PEG)-modified enzymes;
• in the synthesis of poly(PDL-GA) copolymers, via enzymatic catalysis.

General Description

Ethyl glycollate is an ester. Microwave spectra of ethyl glycollate and its deuterated species has been reported.

Ethyl glycolate(623-50-7)Related Product Information

• Ethyl S-4-chloro-3-hydroxybutyrate
• 2-Hydroxyethyl acrylate
• Ethyl 3-hydroxybutyrate
• Ethyl bromoacetate
• Ethyl acrylate
• Ethanol
• Ethyl acetate
• Methyl acrylate
• Diethyl maleate
• Ethyl propiolate
• POLY(2-HYDROXYACETIC ACID)
• Ethylparaben
• Diethyl malonate
• Sodium glycolate
• Ethyl cyanoacetate
• Trinexapac-ethyl
• Diethyl methylmalonate
• Glycolic acid