Chlorhexidine Diacetate Chemical Properties

Melting point:

153-156°C

storage temp. 

2-8°C

solubility 

H₂O: 15 mg/mL, clear

color 

White to Almost white

Water Solubility 

1.9 g/100 mL (20 ºC)

Merck 

14,2091

InChIKey

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

LogP

4.931 (est)

CAS DataBase Reference

56-95-1(CAS DataBase Reference)

EPA Substance Registry System

Chlorhexidine diacetate (56-95-1)

Safety Information

Hazard Codes 

Xn,Xi,N

Risk Statements 

22-43-36/37/38-50/53

Safety Statements 

36/37-36-26-61-60

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

DU1930000

F 

8-10

HazardClass 

9

PackingGroup 

III

HS Code 

2925294500

Toxicity

LD50 orally in mice: 2 g/kg (Davies)

MSDS

• Language:English Provider:Chlorhexidine acetate
• Language:English Provider:SigmaAldrich

Chlorhexidine Diacetate Usage And Synthesis

Chemical Properties

Chlorhexidine Diacetate is white or almost white, microcrystalline powder

Uses

Chlorhexidine Diacetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. Aqueous solutions of chlorhexidine are most stable within the pH range of 5-8. Above pH 8.0 chlorhexidine base is precipitated and in more acid conditions there is gradual deterioration of activity because the compound is less stable. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Uses

antimicrobial agent in, e.g., cosmetic and disinfection solutions, eye drops, uterine antiseptics, toothpaste, mouthwash, hand and wound deansers.

Uses

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Definition

ChEBI: Chlorhexidine acetate is the acetate salt of chlorhexidine. It is a disinfectant used for bacterial control in hospital, agricultural and domestic environments. It has a role as an antibacterial agent, an antiinfective agent, an antifungal agent and an antifouling biocide. It contains a chlorhexidine.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Chlorhexidine Diacetate(56-95-1)Related Product Information

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