2',3'-DIDEOXY-3'-FLUOROURIDINE Chemical Properties

Melting point:

184-188 °C(lit.)

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water

form 

Solid

pka

9.39±0.10(Predicted)

color 

White to Off-White

optical activity

[α]20/D +10.5°, c = 0.5 in 1 M NaOH

BRN 

6064366

Safety Information

Hazard Codes 

Xn

Risk Statements 

68

Safety Statements 

22-36/37

WGK Germany 

1

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

2',3'-DIDEOXY-3'-FLUOROURIDINE Usage And Synthesis

Chemical Properties

Off-white solid

Uses

2'',3''-Dideoxy-3''-fluorouridine is a reactant used in the synthesis of 5''-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.

Uses

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

• 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
• 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

General Description

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

2',3'-DIDEOXY-3'-FLUOROURIDINE(41107-56-6)Related Product Information

• 3'-Deoxy-3'-fluorothymidine
• 2',3'-DIDEOXY-3'-FLUOROURIDINE
• 3'-Deoxy-3'-fluoro-5'-O-trityl-D-thymidine
• 5'-O-ACETYL-2'-3'-DIDEOXY-3'-FLUORO-URIDINE
• 5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE
• FOSALVUDINE TIDOXIL
• 2',3'-dideoxy-5-fluorouridine
• 3'-Azido-2',3'-dideoxy-5-fluorouridine
• 5-fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate
• 5'-O-Benzoyl-3'-fluoro-2',3'-dideoxyuridine
• AURORA KA-635
• 5'-O-Anisoyl-3'-fluoro-2',3'-dideoxyuridine
• 3'-Fluoro-5'-O-toluoyl-2',3'-dideoxyuridine
• 3'-FLUORO 3'-DEOXYTHYMIDINE, [METHYL-3H(N)]-
• AURORA KA-625
• AURORA KA-603
• 5'-O-t-Butyldimethylsilyl-3'-fluoro-2',3'-dideoxyuridine
• AURORA KA-624