2,4-Dichlorotoluene Chemical Properties

Melting point:

-14 °C

Boiling point:

200 °C (lit.)

Density 

1.246 g/mL at 25 °C (lit.)

vapor pressure 

4 hPa (50 °C)

refractive index 

n20/D 1.546(lit.)

Flash point:

175 °F

storage temp. 

Store below +30°C.

form 

Liquid

color 

Clear colorless

Water Solubility 

immiscible

BRN 

1931691

CAS DataBase Reference

95-73-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 2,4-dichloro-1-methyl-(95-73-8)

EPA Substance Registry System

2,4-Dichlorotoluene (95-73-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25

RIDADR 

UN 2810

WGK Germany 

2

RTECS 

XT0730000

Autoignition Temperature

>450 °C

Hazard Note 

Harmful

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29036990

Hazardous Substances Data

95-73-8(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 2400 mg/kg

MSDS

• Language:English Provider:2,4-Dichloro-1-methylbenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4-Dichlorotoluene Usage And Synthesis

Chemical Properties

It is a clear colorless liquid that is insoluble in water but can be mixed with ethanol, ether, and benzene. It is primarily used as a pesticide and pharmaceutical intermediate, but also serves as a solvent.

Uses

2,4-Dichlorotoluene was used as an oxidant and a solvent during anaerobic catalytic oxidation of secondary alcohols by using an in situ (N-heterocyclic carbene)-Ni(0) system. It was used as growth supplement in the culture media of Ralstonia sp. strain PS12. It was used to develop a sensitive method based on solid-phase microextraction followed by gas chromatography-tandem mass spectrometry for the analysis of chlorotoluenes in water samples.

Preparation

2,4-Dichlorotoluene is synthesized by diazotization and chlorination with 2,4-diaminotoluene as raw material. First, hydrochloric acid and water into the reaction pot, heated to 50°C, stirring under the dissolution of 2,4-diaminotoluene, then hydrochloric acid and cuprous chloride into the pot, the 1% sodium nitrite solution evenly added, the temperature is maintained at about 60°C, resting stratification, the lower layer of crude product washed with water to neutral, add alkali to alkaline, and then water to remove the alkali, divided 2,4-dichlorotoluene crude product, water distillation of finished products.

Definition

ChEBI: 2,4-Dichlorotoluene is a dichlorobenzene.

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 2759, 1991 DOI: 10.1016/0040-4039(91)85078-J

General Description

Clear colorless liquid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 2,4-Dichlorotoluene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Purification Methods

Recrystallise 2,4-dichlorotoluene from EtOH at low temperature or fractionally distil it. [Beilstein 5 IV 815.]

2,4-Dichlorotoluene(95-73-8)Related Product Information

• Xylene
• 2',4'-Dichloroacetophenone
• 1,2-Dichloroethane
• p-Toluenesulfonic acid
• 2,4-Dichlorophenol
• 2,4-Dichlorobenzoic acid
• Dichloroethane
• ALPHA,ALPHA-DICHLOROTOLUENE (BENZAL CHLORIDE),α,α-dichlorotoluene benzylidene chloride benzal chloride
• 2,4-Dichlorobenzyl chloride
• 2,4-Dichlorobenzyl alcohol
• 2',3',4'-TRICHLOROACETOPHENONE
• 2,4-Dichlorobenzaldehyde
• 1,2-Dichloro-4-(chloromethyl)benzene
• 3,5-DICHLOROTOLUENE, 98+%
• 3,4-DICHLOROTOLUENE OEKANAL, 250 MG,3,4-Dichlorotoluene97%,3,4-Dichlorotoluene,98%
• 2,6-DICHLOROTOLUENE, 99+%,2,6-DICHLOROTOLUENE OEKANAL, 250 MG
• Toluene
• 2,3-DICHLOROTOLUENE,2,3-DICHLOROTOLUENE OEKANAL, 250 MG,2,3-DICHLOROTOLUENE 98+%