Flutropium bromide Chemical Properties

Melting point:

192-193° (dec); mp 198-199° (dec)

Safety Information

Toxicity

LD50 in male, female mice, male, female rats (mg/kg): 12.5, 11.0, 16.4, 18.4 i.v.; 760, 810, 830, 740 orally (Bauer, Fügner)

Flutropium bromide Usage And Synthesis

Description

Flutropium bromide is an antitussive useful in the treatment of allergic rhinitis and in the symptomatic relief of bronchial asthma and chronic bronchitis. Recent studies suggest that flutropium bromide may have potential as a long-acting alternative to P-sympathomimetics or the xanthines in the prophylaxis of obstructive airways disease.

Originator

Boehringer Ingelheim (W.Germany)

Definition

ChEBI: Flutropium bromide is the organic bromide salt of flutropium. It is used in Japan for the treatment asthma and chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist, an antispasmodic drug and an anti-asthmatic drug. It contains a flutropium.

brand name

Flubron

Flutropium bromide(63516-07-4)Related Product Information

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• Diphenylphosphine
• Sodium bromate
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• Methyl acrylate
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• tert-Butylchlorodiphenylsilane
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• Ethidium bromide
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• Diphenylmethane
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• CHLOROPHOSPHONAZO III