(2,3-epoxyphytyl)menaquinone Chemical Properties

storage temp. 

-20°C

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly)

Boiling point:

561.1±50.0 °C(Predicted)

Density 

1.019±0.06 g/cm3(Predicted)

form 

Oil

color 

Colourless to Pale Yellow

InChI

InChI=1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3

InChIKey

KUTXFBIHPWIDJQ-UHFFFAOYSA-N

SMILES

O1C2(CC=C(C)CCCC(C)CCCC(C)CCCC(C)C)C(=O)C3=C(C(=O)C12C)C=CC=C3

(2,3-epoxyphytyl)menaquinone Usage And Synthesis

Description

Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K₁ 2,3-epoxide is the inactive metabolite of vitamin K₁. During clotting, vitamin K₁ is converted to this epoxide form and then rapidly reduced back to the vitamin by a microsomal epoxide reductase. This is referred to as the vitamin K epoxide cycle. Certain anticoagulants target clotting factor synthesis by inhibiting the recycling of vitamin K₁ from the inactive epoxide.

Chemical Properties

Clear Colourless to Pale Yellow Oil

Uses

A metabolite of Vitamin K1 (V676080).

Biochem/physiol Actions

Vitamin K1 2,3-epoxide is a vitamin K derivative. It is a fat soluble vitamin produced by plants. Vitamin K is essential for blood coagulation. Vitamin K is rarely deficient in a human diet since it is continually recycled in our cells. Vitamin K 2,3-epoxide acts as a substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Elevated levels of serum vitamin K epoxide in patients is associated with familial multiple coagulation factor deficiency.

References

[1] IA CHOONARA. The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activity with warfarin.[J]. British journal of clinical pharmacology, 1988, 25 1: 1-7. DOI: 10.1111/j.1365-2125.1988.tb03274.x

(2,3-epoxyphytyl)menaquinone(25486-55-9)Related Product Information

• Vitamin K1-d7
• Vitamin K1-[13C6] (Phytonadione)
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• 1A,7A-DIHYDRONAPHTHO[2,3-B]OXIRENE-2,7-DIONE
• 1-PHENYL-HEX-5-EN-3-OL
• PHENYLETHYL OXYACETALDEHYDE
• TETRAMETHYLETHYLENE OXIDE
• 2-Methyl-1-tetralone