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N-isopentyladenosine
N-isopentyladenosine Basic information
- Product Name:
- N-isopentyladenosine
- Synonyms:
-
- N-isopentyladenosine
- N-(3-Methylbutyl)adenosine
- Adenosine, N-(3-methylbutyl)-
- Einecs 241-638-1
- N-(3-Methylbutyl)adenosine, N6-Isoamyladenosine
- N6-(3-Methylbutyl)adenosine
- (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(isopentylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
- N6-Isoamyladenosine
- CAS:
- 17659-78-8
- MF:
- C15H23N5O4
- MW:
- 337.37
- EINECS:
- 241-638-1
- Mol File:
- 17659-78-8.mol
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N-isopentyladenosine Chemical Properties
- Boiling point:
- 632.9±65.0 °C(Predicted)
- Density
- 1.57
- pka
- 13.12±0.70(Predicted)
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N-isopentyladenosine Usage And Synthesis
Uses
N-(3-Methylbutyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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