4-(Methylamino)butyric acid Chemical Properties

Melting point:

150-152°C

Boiling point:

237.3±23.0 °C(Predicted)

Density 

1.023±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

pka

4.42±0.10(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

EPA Substance Registry System

Butanoic acid, 4-(methylamino)- (1119-48-8)

4-(Methylamino)butyric acid Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A GABA derivative and hydrolysis product of the industrial solvent, N-methyl-2-pyrrolidinone. Biologically it is a product of nicotine catabolism in bacteria and inhibits L-Carnitine from undergoing β -oxidation in mammals. It is commonly found in skin products to prevent wrinkles.

Definition

ChEBI: 4-(methylamino)butyric acid is a gamma-amino acid comprising that is GABA in which one of the hydrogens attached to the nitrogen is replaced by a methyl group. It is functionally related to a butyric acid and a gamma-aminobutyric acid. It is a conjugate acid of a 4-(methylamino)butyrate. It is a tautomer of a 4-(methylamino)butyric acid zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 896, 1949 DOI: 10.1021/ja01171a037

4-(Methylamino)butyric acid(1119-48-8)Related Product Information

• P-NITROBENZOYL-L-GLUTAMIC ACID
• N-Acetyl-L-glutamic acid
• Ethyl 4-piperidinecarboxylate
• N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER
• N-Cbz-L-glutamic acid
• H-GAMMA-GLU-GLU-OH
• 3-Carboxy-2,2,5,5-tetraMethylpyrrolidine 1-Oxyl Free Radical
• HYDANTOIN-5-ACETIC ACID
• Isonipecotic acid
• Aspartame
• Calcium folinate
• GLYCYL-L-GLUTAMIC ACID
• DL-DIHYDROOROTIC ACID
• 3-[2-(DIETHYLAMINO)ETHYL]-7-HYDROXY-4-METHYLCOUMARIN HYDROCHLORIDE
• Methyl 1-Benzyl-5-oxopyrrolidine-3-carboxylate
• N-(4-NITROBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER
• D(-)-AMETHOPTERIN HYDRATE, 98
• LABOTEST-BB LT00053078