9-CYCLOPENTYLADENINE MONOMETHANESULFONATE Chemical Properties

Melting point:

180-183 °C(lit.)

storage temp. 

room temp

solubility 

H2O: soluble5mg/mL, clear

form 

powder

color 

white to beige

Water Solubility 

H2O: 5mg/mL, clear

Safety Information

WGK Germany 

3

RTECS 

AU6255000

9-CYCLOPENTYLADENINE MONOMETHANESULFONATE Usage And Synthesis

Uses

9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties[1][2].

Biological Activity

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor th at targets the P-site domain. IC50 = 100 μM in detergent-dispersed r at brain preparation.

References

[1] Ulrike Riese，et al. Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways. FEBS Lett. 2004 Nov 19;577(3):455-9. DOI:10.1016/j.febslet.2004.10.045
[2] Eglantina Idrizaj，et al. Relaxin influences ileal muscular activity through a dual signaling pathway in mice. World J Gastroenterol. 2018 Feb 28;24(8):882-893. DOI:10.3748/wjg.v24.i8.882
[3] Mitsuhiro Denda, et al. Association of cyclic adenosine monophosphate with permeability barrier homeostasis of murine skin. J Invest Dermatol. 2004 Jan;122(1):140-6. DOI:10.1046/j.0022-202X.2003.22115.x

9-CYCLOPENTYLADENINE MONOMETHANESULFONATE(189639-09-6)Related Product Information

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