D-SACCHARIC ACID 1 4-LACTONE Chemical Properties

Melting point:

80-82°C

storage temp. 

2-8°C

solubility 

Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

BRN 

85594

Safety Information

WGK Germany 

3

HS Code 

29322090

D-SACCHARIC ACID 1 4-LACTONE Usage And Synthesis

Chemical Properties

White Solid

Uses

Anticancer agent.

Uses

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.

General Description

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

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