TRIS(3-AMINOPROPYL)AMINE Chemical Properties

Boiling point:

150 °C / 3mmHg

Density 

0,95 g/cm³

refractive index 

1.4920 to 1.4950

storage temp. 

2-8°C, protect from light

pka

10.62±0.10(Predicted)

form 

clear liquid

color 

Colorless to Light yellow

InChI

InChI=1S/C9H24N4/c10-4-1-7-13(8-2-5-11)9-3-6-12/h1-12H2

InChIKey

QMXSDTGNCZVWTB-UHFFFAOYSA-N

SMILES

C(N(CCCN)CCCN)CCN

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

2735

HS Code 

2921.29.0055

HazardClass 

8

PackingGroup 

III

TRIS(3-AMINOPROPYL)AMINE Usage And Synthesis

Synthesis

General procedure for the synthesis of tris(3-aminopropyl)amine from 3,3',3''-hypromellitic acid tripropionitrile: 17.6 g of tris(3-nitropropyl)amine, 7.5 g of NaOH, 25 mL of hydrazine hydrate and 100 mL of ethanol were added to a three-necked round-bottomed flask at 0 °C, and 5.0 g of Raney Ni was added slowly.The progress of the reaction was monitored during the course of the reaction by thin layer chromatography (TLC). The progress of the reaction was monitored by thin layer chromatography (TLC) during the reaction. Upon completion of the reaction, the reaction mixture was recovered by filtration, pH was adjusted to 1-12 and left to stand to separate the salt. Subsequently, the obtained clarified yellow liquid was vacuum distilled to collect the fraction at 120-125°C. The yield was 92%. The product was characterized by 1H NMR (CDCl3) and IR spectroscopy: 1H NMR (CDCl3): δ 1.42 (d, 6H); 2.45 (t, J=5.8Hz, 6H); 1.58 (tt, J=5.8Hz, 5.6Hz, 6H); 2.70 (t, J=5.6Hz, 6H). ir (cm-1): 3346. 3288, 2862, 1575, 1471, 1315, 819.

References

[1] Materials Research Bulletin, 2014, vol. 56, p. 12 - 18
[2] Angewandte Chemie, 1993, vol. 105, # 9, p. 1367 - 1370
[3] Journal of the American Chemical Society, 1945, vol. 67, p. 1995
[4] Helvetica Chimica Acta, 1979, vol. 62, p. 2763 - 2787
[5] Journal of the American Chemical Society, 1989, vol. 111, # 1, p. 186 - 190

TRIS(3-AMINOPROPYL)AMINE(4963-47-7)Related Product Information

• N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine
• 3,3',3''-NITRILOTRIS(PROPIONAMIDE)
• DODECAHYDRO-1,4,7,9B-TETRAAZOPHENALENE
• TETRAKIS(3-AMINOPROPYL)-1,3-PROPANEDIAMINE
• TRIS(3-AMINOPROPYL)AMINE