ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Borane > (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Basic information
- Product Name:
- (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
- Synonyms:
-
- (S)-1-METHYL-3,3-DIPHENYL-TETRAHYDRO-PYRROLO[1,2C][1,3,2]OXAZABOROLE
- α,α-diphenyl-l-prolinol methylboronic acid cycl-amide-ester
- (S)-(+)-Methyl-CBS-oxazaborolidine
- (S)-1-METHYL-3,3-DIPHENYLHEXAHYDROPYRROLO[1,2-C][1,3,2]OXAZABOROLE
- (S)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE 98+%
- (S)-METHYL-CBS-OXAZABOROLIDINE,1M SOLN.IN TOLUENE
- (S)-Me-CBS Catalyst
- (S)-Methyl oxazaborolidine, in toluene, 1M solution
- CAS:
- 112022-81-8
- MF:
- C18H20BNO
- MW:
- 277.17
- EINECS:
- 601-150-5
- Product Categories:
-
- organic or inorganic borate
- API intermediates
- Asymmetric Synthesis
- B (Classes of Boron Compounds)
- B-Bromocatecholborane, etc.
- Synthetic Organic Chemistry
- Asymmetric Synthesis
- Chiral Catalysts, Ligands, and Reagents
- Reduction
- Mol File:
- 112022-81-8.mol
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Chemical Properties
- Melting point:
- 115-117°C
- Boiling point:
- 111 °C
- Density
- 0.93 g/mL at 20 °C(lit.)
- refractive index
- -68 ° (C=1, MeOH)
- Flash point:
- 40 °F
- storage temp.
- room temp
- form
- Liquid
- pka
- 1.02±0.40(Predicted)
- color
- Colorless to amber
- Water Solubility
- Hydrolyzes in water.
- Sensitive
- Air & Moisture Sensitive
- BRN
- 8492123
- Exposure limits
- ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) - InChIKey
- VMKAFJQFKBASMU-KRWDZBQOSA-N
- CAS DataBase Reference
- 112022-81-8(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi,Xn,F
- Risk Statements
- 36/37/38-67-65-63-48/20-11-19-40
- Safety Statements
- 26-62-36/37-33-29-16
- RIDADR
- UN 1294 3/PG 2
- WGK Germany
- 3
- F
- 10-21
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29349990
MSDS
- Language:English Provider:(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Usage And Synthesis
Reaction
- Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures.
- Asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines.
- Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: Stereospecific formation of diarylalkanes and triarylmethanes.
- Enantioselective reduction of prochiral ketones with NaBH4/Me2SO4/(S)-Me-CBS.
Chemical Properties
Colorless to yellow liquid
Uses
(S)-2-Methyl-CBS-oxazaborolidine is used as an oxazaborolidine catalyst. It is also employed in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols and propargyl alcohols. It is an anhydrous catalyst for 'CBS' reduction reaction.
Uses
suzuki reaction
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Preparation Products And Raw materials
Raw materials
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaboroleSupplier
Shanghai Forxine Pharmaceutical Co., Ltd. Gold
- Tel
- 21-21-64961388 18918697718
- service@forxine.com
Viwit Pharmaceutical Co., Ltd. Gold
- Tel
- 0632-2980981 15063270987
- service.china3@viwit.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole(112022-81-8)Related Product Information
- (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
- Phosphorus trichloride
- 4-Methoxybenzoic acid
- Lithium hydride
- Tetrahydrofuran
- CATECHOLBORANE
- (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol
- L-(+)-Prolinol
- Methylboronic acid
- (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
- (R)-Tetrahydro-1,3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole, 99% (R)-Phenyl oxazaborolidine
- (S)-O-TOLYL-CBS-OXAZABOROLIDINE, 0.5M I&
- (S)-Tetrahydro-1,3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole, 99% (S)-Phenyl oxazaborolidine
- (S)-CBS-BORANE COMPLEX
- (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
- (R)-O-TOLYL-CBS-OXAZABOROLIDINE, 0.5M I&