JP1302
JP1302 Basic information
- Product Name:
- JP1302
- Synonyms:
-
- JP1302
- 9-Acridinamine, N-(4-(4-methyl-1-piperazinyl)phenyl)-
- Brn 5117597
- N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine
- JP 1302 dihydrochloride
- N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride
- JP1302(9-Acridinamine, N-[4-(4-methyl-1-piperazinyl)phenyl]-)
- MMV006172
- CAS:
- 80259-18-3
- MF:
- C24H24N4
- MW:
- 368.47
- Product Categories:
-
- Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.
- Mol File:
- 80259-18-3.mol
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JP1302 Chemical Properties
- Boiling point:
- 550.9±50.0 °C(Predicted)
- Density
- 1.227±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at -20°C
- pka
- 9.03±0.10(Predicted)
- Water Solubility
- <44.14mg/ml in Water
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JP1302 Usage And Synthesis
Uses
JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
Biological Activity
α 2C -adrenoceptor antagonist that displays ~ 50-fold selectivity over other α 2 -adrenoceptor subtypes (K i values are 28, 1470, 1700 and 3150 nM for human α 2C , α 2B , α 2D and α 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35 GTP γ S binding in vitro (K B = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo .
JP1302Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
VDM Biochemicals
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- 0330-2528181
- sales@vdmbio.com
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696，15000506266 15000506266
Shanghaizehan biopharma technology co., Ltd.
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- 021-61350663 13052117465
- sales@zehanbiopharma.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com