Histatin 5
Histatin 5 Basic information
- Product Name:
- Histatin 5
- Synonyms:
-
- Histatin 5 (synthetic human re-Hst5)
- Human histatin 5
- Peptide F-A (human parotid saliva)
- L-Tyrosine, L-α-aspartyl-L-seryl-L-histidyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-histidylglycyl-L-tyrosyl-L-lysyl-L-arginyl-L-lysyl-L-phenylalanyl-L-histidyl-L-α-glutamyl-L-lysyl-L-histidyl-L-histidyl-L-seryl-L-histidyl-L-arginylglycyl-
- CAS:
- 115966-68-2
- MF:
- C133H195N51O33
- MW:
- 3036.29
- Mol File:
- 115966-68-2.mol
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Histatin 5 Chemical Properties
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- Sequence
- Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr
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Histatin 5 Usage And Synthesis
Uses
Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
References
[1] Gusman H, et al. Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontaldisease. Infect Immun. 2001 Mar;69(3):1402-8. DOI:10.1128/IAI.69.3.1402-1408.2001
[2] Helmerhorst EJ, et al. The human salivary peptide histatin 5 exerts its antifungal activity through the formation ofreactive oxygen species. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14637-42. DOI:10.1073/pnas.141366998
Histatin 5Supplier
Shanghai Macklin Biochemical Co.,Ltd.
- Tel
- 15221275939
- shenlinxing@macklin.cn
Creative Peptides
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- info@creative-peptides.com
Nanjing Leon Biological Technology Co., Ltd.
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- 17705183659
- sales@njleonbiotech.com
Nanjing Peptide Biotech Ltd.
- Tel
- 025-58361106-805 15951641583
- zhao.xu@njpeptide.com
Chengdu Youngshe Chemical Co., Ltd.
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- +86-17380623303
- Caroline@youngshechem.com