Basic information Safety Supplier Related

Phenylacetic acid-4-boronic acid pinacol ester

Basic information Safety Supplier Related

Phenylacetic acid-4-boronic acid pinacol ester Basic information

Product Name:
Phenylacetic acid-4-boronic acid pinacol ester
Synonyms:
  • 4-(Carboxymethyl)phenylboronic acidpinacol ester
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid
  • 4-(Carboxymethyl)phenylboronic acid pinacol ester 95%
  • [4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]acetic acid
  • 2-[4-(Carboxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • Benzeneacetic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS:
797755-07-8
MF:
C14H19BO4
MW:
262.11
Product Categories:
  • Boronic ester
  • Organoborons
  • Aryl
Mol File:
797755-07-8.mol
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Phenylacetic acid-4-boronic acid pinacol ester Chemical Properties

Melting point:
165-170°C
Boiling point:
398.2±25.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.24±0.10(Predicted)
form 
Crystalline Powder or Powder
color 
White to yellow
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
1
HazardClass 
IRRITANT
HS Code 
2931900090
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Phenylacetic acid-4-boronic acid pinacol ester Usage And Synthesis

Uses

4-(Carboxymethyl)phenylboronic acid pinacol ester can be used:

  • As an intermediate to prepare hydantoin-derived autotaxin inhibitors.
  • As a substrate in the synthesis of reactive oxygen species (ROS)-sensitive and H2O2-eliminating materials by interlinking phenylboronic acid pinacol esters onto β-cyclodextrin.
  • To prepare 5-aryl-2-aminopyridine derived FLT3 kinase inhibitors.

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