Bromindione Chemical Properties

Melting point:

139-142°C

Density 

1.4993 (rough estimate)

refractive index 

1.4650 (estimate)

storage temp. 

Amber Vial, -20°C Freezer

solubility 

Chloroform, Methanol

form 

Solid

color 

Black

Stability:

Light Sensitive

Safety Information

RIDADR 

2811

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

2914199090

Toxicity

LD50 oral in mouse: 200mg/kg

Bromindione Usage And Synthesis

Chemical Properties

Black Solid

Originator

Bromindione,Chemical Formulations

Uses

antidiabetic

Uses

Anticoagulant.

Definition

ChEBI: Bromindione is a member of indanones and a cyclic ketone.

Manufacturing Process

To a solution of 1.85 g of sodium in 40 ml of ethanol, was added 10 g of phthalide and 14.0 g of p-bromobenzaldehyde, and the reaction mixture was heated on the steam bath for one hour. Water was then added, and the alcohol was distilled off. Then after adding additional water, the reaction mixture was acidified with hydrochloric acid to precipitate the crude product, which was filtered off, dried and recrystallized from methanol. The 2-pbromophenylindandione is in the form of dark red crystals, having a melting point of 133-135°C.

Therapeutic Function

Anticoagulant

Bromindione(1146-98-1)Related Product Information

• 2-(4-BROMOPHENYL)ACETOPHENONE
• TCID
• (4-BROMO-PHENYL)-ACETALDEHYDE
• 3-Phenyl-2,4-pentanedione
• 4-Bromocumene
• Bromindione
• 2-(4-BROMOPHENYL)MALONDIALDEHYDE
• 2-phenyl-2,3-dihydroinden-1-one
• 1-Indanone
• 2'-METHYL-2-PHENYLACETOPHENONE
• 4-Bromophenylacetone
• 2-PHENYL-1,3-INDANDIONE