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Curdione

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Curdione Basic information

Product Name:
Curdione
Synonyms:
  • (3S,6E,10S)-6,10-Dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione
  • Curdione
  • Germacr-1(10)-ene-5,8-dione
  • 6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione
  • AaruginousTurmericRhizome
  • Curcuma two ketone
  • Curdione, >99%
  • Curcuma Tuber Extract
CAS:
13657-68-6
MF:
C15H24O2
MW:
236.35
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
13657-68-6.mol
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Curdione Chemical Properties

Melting point:
61.5-62.0 °C
Boiling point:
318.82°C (rough estimate)
Density 
0.93
refractive index 
1.4700 (estimate)
Flash point:
130℃
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form 
Cryst.
color 
White to off-white
LogP
3.120 (est)
NIST Chemistry Reference
6,10-Dimethyl-3-(1-methylethyl)-6-cyclodecene-1,4-dione(13657-68-6)
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Safety Information

HS Code 
29143990
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Curdione Usage And Synthesis

Chemical Properties

Colorless prismatic crystal (anhydrous ethanol), melting point 61~62℃, [α]25D+26°(c=1, chloroform), easily soluble in ether and chloroform, slightly soluble in petroleum ether.

Uses

Curdione can be used for content determination, identification and pharmacological experiments, etc. Pharmacological and pharmacological effects: It has obvious inhibitory effect on mouse sarcoma 37, mouse cervical cancer U14 and mouse Ehrlich ascites cancer, and can make cancer cells cross necrosis. Ehrlich ascites carcinoma treated with this product can successfully obtain active immunity in mice. It has good curative effect in clinical treatment of cervical cancer.

Definition

ChEBI: Curdione is a germacrane sesquiterpenoid.

Biological Activity

Curdione is a sesquiterpenoid substance isolated from Curcuma zedoary, with high biological activity, which has the effect of inhibiting platelet aggregation and resisting thrombosis.

CurdioneSupplier

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0411-62910999 13889544652
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