Curdione
Curdione Basic information
- Product Name:
- Curdione
- Synonyms:
-
- (3S,6E,10S)-6,10-Dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione
- Curdione
- Germacr-1(10)-ene-5,8-dione
- 6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione
- AaruginousTurmericRhizome
- Curcuma two ketone
- Curdione, >99%
- Curcuma Tuber Extract
- CAS:
- 13657-68-6
- MF:
- C15H24O2
- MW:
- 236.35
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 13657-68-6.mol
Curdione Chemical Properties
- Melting point:
- 61.5-62.0 °C
- Boiling point:
- 318.82°C (rough estimate)
- Density
- 0.93
- refractive index
- 1.4700 (estimate)
- Flash point:
- 130℃
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- Cryst.
- color
- White to off-white
- LogP
- 3.120 (est)
- NIST Chemistry Reference
- 6,10-Dimethyl-3-(1-methylethyl)-6-cyclodecene-1,4-dione(13657-68-6)
Curdione Usage And Synthesis
Chemical Properties
Colorless prismatic crystal (anhydrous ethanol), melting point 61~62℃, [α]25D+26°(c=1, chloroform), easily soluble in ether and chloroform, slightly soluble in petroleum ether.
Uses
Curdione can be used for content determination, identification and pharmacological experiments, etc. Pharmacological and pharmacological effects: It has obvious inhibitory effect on mouse sarcoma 37, mouse cervical cancer U14 and mouse Ehrlich ascites cancer, and can make cancer cells cross necrosis. Ehrlich ascites carcinoma treated with this product can successfully obtain active immunity in mice. It has good curative effect in clinical treatment of cervical cancer.
Definition
ChEBI: Curdione is a germacrane sesquiterpenoid.
Biological Activity
Curdione is a sesquiterpenoid substance isolated from Curcuma zedoary, with high biological activity, which has the effect of inhibiting platelet aggregation and resisting thrombosis.
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- Curdione