Demethyl-Coclaurine Chemical Properties

Melting point:

208-210 °C

Boiling point:

522.4±50.0 °C(Predicted)

Density 

1.317±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

9.72±0.40(Predicted)

color 

White to Off-White

Demethyl-Coclaurine Usage And Synthesis

Uses

(±)-Norcoclaurine can be used to prevent and treat of Alzheimer’s disease, bind to SARS-CoV-2 S protein:human ACE2 complex, as a bronchodilator to improve lung function in various respiratory diseases, and an antioxidant in lipid-like environments. It can also be used as a racemic salt-acidic compound to produce elevated and sustained ketosis.

Uses

Demethyl-Coclaurine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.

Definition

ChEBI: (RS)-norcoclaurine is a norcoclaurine. It is a conjugate base of a (RS)-norcoclaurinium.

Demethyl-Coclaurine(5843-65-2)Related Product Information

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• D-TUBOCURARINE CHLORIDE
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• Tetrahydropapaverine hydrochloride
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• DL-LAUDANOSINE
• BERBAMINE
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• TETRAHYDROBERBERINE
• AKOS 236-50