1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-(-)-2-(dimethylamino)cyclohexyl]thiourea(R,R-TUC) Chemical Properties

Melting point:

87-88°C

alpha 

-42° (c 1.05, CHCl3)

Boiling point:

380.8±52.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

pka

11.76±0.70(Predicted)

form 

Powder

color 

white

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-(-)-2-(dimethylamino)cyclohexyl]thiourea(R,R-TUC) Usage And Synthesis

Reaction

1. Thiourea catalyst used in the enantio and diastereoselective Michael addition of malonates and ketoesters to nitroolefins.
2. Catalyst used in the enantioselective hydrazination of 1,3-dicarbonyl compounds.
3. Catalyst used for the dynamic resolution of azalactones.
4. Catalyst used in Michael-Aldol reaction of 2-mercaptobenzaldehyde with α,β-unsaturated oxazolidinone.
5. Catalyst for enantioselective synthesis of flavanones and chromanones.
6. Catalyst for the asymmetric Neber Reaction.
7. Catalyst for the three component synthesis of 2,6-diazabicyclo[2.2.2]octanones. 

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-(-)-2-(dimethylamino)cyclohexyl]thiourea(R,R-TUC)(620960-26-1)Related Product Information

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