7-Hydroxy-5-methyl-1,3,4-triazaindolizine Chemical Properties

Melting point:

280-283 °C(lit.)

Boiling point:

271.66°C (rough estimate)

Density 

1.3471 (rough estimate)

vapor pressure 

0-0Pa at 20-25℃

refractive index 

1.6700 (estimate)

storage temp. 

2-8°C

pka

1.14±0.53(Predicted)

color 

White to Almost white

Water Solubility 

INSOLUBLE IN COLD WATER

BRN 

609440

InChIKey

ZUIVNYGZFPOXFW-UHFFFAOYSA-N

LogP

-1.4 at 19℃ and pH7.1

CAS DataBase Reference

2503-56-2(CAS DataBase Reference)

NIST Chemistry Reference

Pyrimidin-7-ol, 5-methyl-s-triazolo-[1,5-a]-(2503-56-2)

EPA Substance Registry System

[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl- (2503-56-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

1

RTECS 

XZ6133300

F 

9

Hazard Note 

Harmful

TSCA 

Yes

HS Code 

2933998090

Toxicity

mouse,LD50,intravenous,> 450mg/kg (450mg/kg),Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 597, 1977.

MSDS

• Language:English Provider:7-Hydroxy-5-methyl-1,3,4-triazaindolizine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Usage And Synthesis

Chemical Properties

7-Hydroxy-5-methyl-1,3,4-triazaindolizine is white fine crystalline powder

Uses

Reactant for the synthesis of: • ;Ruthenium(II)-Hmtpo complexes1• ;Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5

Uses

Reactant for the synthesis of:

• Ruthenium(II)-Hmtpo complexes
• Dihydroorotate dehydrogenase inhibitors with antimalarial activity

Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles

Investigations of the pharmacological activity caused by binding to HIV TAR RNA

Additive to study the space charge layer in silver bromide microcrystals

7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2)Related Product Information

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