1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Chemical Properties

solubility 

DMF: >125 μg/ml; DMSO: <20 μg/ml; Ethanol: >10 mg/ml; PBS pH 7.2: >11 mg/ml

form 

A lyophilized powder

1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE Usage And Synthesis

Description

2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP. 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.

Definition

ChEBI: 2-O-ethyl PAF C-16 is a glycerophosphocholine and an ether lipid.

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