Ligustrazine Hydrochloride Chemical Properties

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml

form 

powder

color 

White

Ligustrazine Hydrochloride Usage And Synthesis

Description

Ligustrazine Hydrochloride, its main function is to inhibit platelet aggregation and prevent thrombosis. At the same time, it can resist vascular damage caused by serotonin and bradykinin, increase capillary resistance, reduce capillary permeability, and prevent edema caused by increased vascular permeability. Clinically, it is mainly used for occlusive syndrome, thrombophlebitis, capillary bleeding, etc. The market demand for this product is large.

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dried root of Ligusticum chuanxiong hort.

Uses

Ligustrazine Hydrochloride has the effect of antiplatelet coagulation, dilation of small arteries, treatment of occlusive cerebrovascular disease.

Application

Ligustrazine Hydrochloride can be used to treat cerebral insufficiency, cerebral thrombosis, cerebral embolism and other ischemic vascular diseases, such as coronary atherosclerotic heart disease, vasculitis, etc. When the patient is in the acute stage of the disease, intravenous drip is generally used.

target

IL Receptor | NOS | NO | TGF-β/Smad | TXA2 - PGI2 | VEGFR

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