5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine Chemical Properties

Density 

1.35±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in acetonitrile

pka

9.16±0.20(Predicted)

form 

Powder

color 

White to Pale Yellow

InChI

InChI=1/C36H39N5O8/c1-21(2)32(43)39-35-38-31-28(33(44)40-35)37-20-41(31)34-30(47-5)29(42)27(49-34)19-48-36(22-9-7-6-8-10-22,23-11-15-25(45-3)16-12-23)24-13-17-26(46-4)18-14-24/h6-18,20-21,27,29-30,34,42H,19H2,1-5H3,(H2,38,39,40,43,44)/t27-,29-,30-,34-/s3

InChIKey

ISQLJOGRNUQHJX-WKLYCMIMNA-N

SMILES

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1O |&1:25,27,44,47,r|

Safety Information

HS Code 

29389090

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine Usage And Synthesis

Description

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.

Chemical Properties

The IUPAC Name is N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide.

Uses

5''-O-DMT-N2-Isobutyryl-2''-O-methyl-D-guanosine (CAS# 114745-26-5) is a guanosine derivative used in the preparation of synthetic RNA derivatives such as native-like crosslinked duplex RNA for use in biochemical and nanotechnology studies.

Biological Activity

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine(114745-26-5)Related Product Information

• 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine
• N2-(2-METHYLPROPANOYL)-GUANOSINE