DIRECT RED 80 Chemical Properties

Density 

1.625[at 20℃]

vapor pressure 

0Pa at 25℃

storage temp. 

room temp

solubility 

DMF: Slightly Soluble
DMSO: Slightly SolublePBS (pH 7.2): 10 mg/ml

form 

powder

Colour Index 

35780

pka

pK1-6 < 2; pK7.8 >13(at 25℃)

color 

Dark green to Dark red to Black

Water Solubility 

Partly soluble in water, very slightly soluble in ethanol, and cellosolve. Insoluble in many organic solvents.

λmax

528 nm

ε(extinction coefficient)

≥12000 at 277-283nm in H2O
≥15000 at 223-235nm in H2O
≥32000 at 524-530nm in H2O

Merck 

14,8548

BRN 

8185575

InChIKey

YIQKLZYTHXTDDT-IJPLDVMMSA-H

LogP

-2.82 at 20℃

CAS DataBase Reference

2610-10-8

EPA Substance Registry System

C.I. Direct Red 80, hexasodium salt (2610-10-8)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

2927.00.3000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

DIRECT RED 80 Usage And Synthesis

Chemical Properties

Reddish brown powder. Soluble in water, solubility in water (60℃) 30g/L. Aqueous solution is bluish red to magenta, adding concentrated hydrochloric acid produces purple precipitate; adding concentrated sodium hydroxide solution is magenta purple. Difficult to dissolve in ethanol, ethylene glycol ether, insoluble in other organic solvents. Blue in concentrated sulfuric acid, bluish red to purple after dilution. Blue in concentrated nitric acid.

Uses

Stain for connective tissue. Dye for cellulose fibers.

Uses

Direct red 80 is a dye useful as a cardiac muscle stain and as a model compound in adsorption studies. It has also been utilized to compare efficacy of textile dye removal in aqueous solutions.

Definition

ChEBI: An organic sodium salt resulting from the formal condensation of Sirius red F3B (acid form) with six equivalents of sodium hydroxide. A polyazo dye used principally in staining methods for collagen and amyloid.

Flammability and Explosibility

Non flammable

Properties and Applications

References

[1] L. C. U. JUNQUEIRA  R. R B  G Bignolas. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections[J]. Journal of Molecular Histology, 1979, 11 4: 447-455. DOI: 10.1007/bf01002772
[2] R W DAPSON. Certification procedures for sirius red F3B (CI 35780, Direct red 80).[J]. Biotechnic & Histochemistry, 2011, 86 3: 133-139. DOI: 10.3109/10520295.2011.570277

DIRECT RED 80(2610-10-8)Related Product Information

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