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Desmethylanhydroicaritin

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Desmethylanhydroicaritin Basic information

Product Name:
Desmethylanhydroicaritin
Synonyms:
  • Desmethylanhydroicaritin
  • 3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone
  • 8-Prenylkaempferol
  • Desmethylicaritin
  • Noranhydroicaritin
  • 8-C-Prenylkaempferol
  • 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
  • 4'-DesMethylicaritin
CAS:
28610-31-3
MF:
C20H18O6
MW:
354.35
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
28610-31-3.mol
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Desmethylanhydroicaritin Chemical Properties

Melting point:
220-222°C
Boiling point:
605.7±55.0 °C(Predicted)
Density 
1.444±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Acetone (Slightly), Methanol (Slightly)
form 
Solid
pka
6.45±0.40(Predicted)
color 
Light Yellow to Yellow
Stability:
Hygroscopic
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Desmethylanhydroicaritin Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells.

target

p38MAPK | NF-kB | PI3K | NO | NOS | AP-1 | JNK | MEK | ERK | IkB | IKK

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