Canthaxanthin Chemical Properties

Melting point:

217～218℃

Boiling point:

717.0±40.0 °C(Predicted)

Density 

1.003±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Chloroform (Slightly)

form 

Solid

color 

Very Dark Red to Black

λmax

λ: 465 nm±5 nm Amax

Merck 

13,1758

BRN 

1898520

Stability:

Light Sensitive

InChIKey

FDSDTBUPSURDBL-DKLMTRRASA-N

LogP

9.526 (est)

CAS DataBase Reference

514-78-3(CAS DataBase Reference)

Safety Information

WGK Germany 

nwg

RTECS 

FI0330000

Canthaxanthin Usage And Synthesis

Uses

Antioxidant immune to promote

Uses

Canthaxanthin is a synthetic red colorant that is the carotenoid of most intense red color. it is available in oil-soluble, oil-dispersible, and water-dispersible forms. it has fair ph, heat, light, and chemical stability with a low tinctorial strength. unlike the carotenoids beta- carotene and beta-apo-8-carotenal, it does not possess vitamin a activity. maximum usage level is 66 ppm. uses include carbonated soft drinks, salad dressing, and spaghetti sauce.

Uses

Permissible color additive for food and drugs (exempt from certification): Fed. Regist. 34, no. 5 (Jan. 8, 1969). Oral suntanning agent.

Definition

ChEBI: A carotenone that consists of beta,beta-carotene bearing two oxo substituents at positions 4 and 4'.

brand name

Apotrin;Phenoro.

World Health Organization (WHO)

Canthaxanthin, a naturally-occurring carotenoid with a deep redorange colour, is widely used as a food colouring agent. Since the mid-1970s it has been included in oral 'artificial suntan' preparations. It is also available in preparations used in the treatment of certain photodermatoses. By the mid-1980s its use in such preparations had been associated with the accumulation of crystalline deposits in the retina. Reported functional changes relating to dark adaptation have been of marginal clinical significance and largely reversible. Nevertheless, this has led to the withdrawal of artificial suntan preparations containing canthaxanthin by several regulatory authorities. Preparations for treatment of photodermatoses remain available in some but not all of these countries.

General Description

Canthaxanthin (red diketocarotenoid or 4, 4′-diketo-β-carotene), is a common xanthophyll found naturally in microorganisms and marine organisms, as well as in certain animals. It acts as an antioxidant in living organisms. The potential antioxidant activity of canthaxanthin is due to the presence of conjugated double bonds in its structure. It finds applications in various fields including poultry, fishery, cosmetics, medicine, and pharmaceuticals. In food industries, canthaxanthin can be used as a coloring agent.

Hazard

Oral intake may cause loss of night vision.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

Properties and Applications

yellow light pink to red yellow light.

Purification Methods

Purify canthaxanthin by chromatography on a column of deactivated alumina or magnesium oxide, or on a thin layer plate of silica gel G (M

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