asebogenin
asebogenin Basic information
- Product Name:
- asebogenin
- Synonyms:
-
- asebogenin
- 1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone
- 4'-O-Methylphloretin
- 1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-
- Asebogenin, 10 mM in DMSO
- Dihydroisosakuranetin
- CAS:
- 520-42-3
- MF:
- C16H16O5
- MW:
- 288.3
- Mol File:
- 520-42-3.mol
More
Less
asebogenin Chemical Properties
- Melting point:
- 168℃
- Boiling point:
- 550.9±50.0 °C(Predicted)
- Density
- 1.325±0.06 g/cm3(Predicted)
- pka
- 7.00±0.40(Predicted)
More
Less
asebogenin Usage And Synthesis
Uses
Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2].
Definition
ChEBI: A member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin.
References
[1] 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. DOI:10.1046/j.1365-3156.1999.00456.x
[2] Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. DOI:10.1111/bph.15964
asebogeninSupplier
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
TransMIT GmbH PlantMetaChem
- Tel
- +49-172-1024293
- pmc@transmit.de
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
ALB Technology Limited
- Tel
- 702-983-3769
- sales@albtechnology.com