Basic information Safety Supplier Related

2,5-dihydroxybenzyl alcohol

Basic information Safety Supplier Related

2,5-dihydroxybenzyl alcohol Basic information

Product Name:
2,5-dihydroxybenzyl alcohol
Synonyms:
  • 2,5-dihydroxybenzyl alcohol
  • 2,5-Dihydroxybenzyl alcohol, Hydroxymethyl-hydrochinone
  • Gentisyl alcohol
  • 2-(Hydroxymethyl)-1,4-benzenediol
  • 2-Hydroxymethyl-1,4-benzenediol
  • 3,6-Dihydroxybenzenemethanol
  • Salirepol
  • 1,4-Benzenediol, 2-(hydroxyMethyl)-
CAS:
495-08-9
MF:
C7H8O3
MW:
140.14
Mol File:
495-08-9.mol
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2,5-dihydroxybenzyl alcohol Chemical Properties

Melting point:
100°
Boiling point:
216.62°C (rough estimate)
Density 
1.2127 (rough estimate)
refractive index 
1.4638 (estimate)
pka
10.46±0.18(Predicted)
LogP
-0.540 (est)
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2,5-dihydroxybenzyl alcohol Usage And Synthesis

Definition

ChEBI: Gentisyl alcohol is an aromatic primary alcohol that is benzyl alcohol substituted by hydroxy groups at positions 2 and 5. It has a role as an antioxidant, an antineoplastic agent, an apoptosis inhibitor and a fungal metabolite. It is an aromatic primary alcohol and a member of phenols. It is functionally related to a benzyl alcohol and a hydroquinone.

Synthesis Reference(s)

Journal of the American Chemical Society, 97, p. 5272, 1975 DOI: 10.1021/ja00851a042

Purification Methods

Crystallise the alcohol from ligroin, CHCl3, AcOH or H2O. Sublime it at ~70o under high vacuum. [Beilstein 6 II 1084, 6 III 6326.]

2,5-dihydroxybenzyl alcoholSupplier

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